MTCC 25308 · Spore-Forming Culture

Introducing Bacospore®.

A standardized, spore-forming Heyndrickxia coagulans MTCC 25308 probiotic, manufactured through controlled fermentation for digestive-health supplements, functional foods and nutraceutical formulations.

Scanning electron microscopy of Bacillus coagulans MTCC 25308 spores
[ Field Note · 01 ]
"The spore coat provides structural defense against acidic and challenging environmental conditions across gastrointestinal passage."
Stable spore-forming Heyndrickxia coagulans MTCC 25308·Formerly known as Bacillus coagulans·Deposited with MTCC India and ATCC (PTA-126364)·Standardized by viable spore count·Manufactured through controlled fermentation·Supports healthy intestinal microflora·Documented at 200B and 300B viable spores per gram·GMO-Free · BSE/TSE-Free · Non-Irradiated · ETO-Free·
Stable spore-forming Heyndrickxia coagulans MTCC 25308·Formerly known as Bacillus coagulans·Deposited with MTCC India and ATCC (PTA-126364)·Standardized by viable spore count·Manufactured through controlled fermentation·Supports healthy intestinal microflora·Documented at 200B and 300B viable spores per gram·GMO-Free · BSE/TSE-Free · Non-Irradiated · ETO-Free·
[ 01 ] Introducing Bacospore®

Stable spore-forming probiotic, engineered by biology.

Bacospore® is a stable, spore-forming probiotic preparation containing Heyndrickxia coagulans, formerly Bacillus coagulans. Unlike many non-spore-forming probiotics, its resistant spores are designed to tolerate acidic and challenging environmental conditions, supporting delivery through the gastrointestinal tract.

Bacospore® is standardized for viable spores and manufactured using a controlled fermentation process. The strain can produce short-chain organic acids, bacteriocin-like substances, exopolysaccharides and digestive enzymes: a profile associated with intestinal microbial balance, digestive comfort, nutrient utilization and gastrointestinal health.

Discover the Bacospore® Strain →
Macro visualization of a Bacillus coagulans spore
Strain Deposit
MTCC 25308 · ATCC PTA-126364
MTCC 25308ATCC PTA-126364GMO FreeBSE / TSE FreeNon-IrradiatedETO-FreeMade in India
[ 02 ] The Bacospore® Reference

Four pillars for the formulator's technical review.

01

Mechanism

Spore survival, microbial balance, lactic acid production, gut-barrier support and beneficial metabolites.

Explore the Mechanism →
02

Research

Laboratory and preclinical research on MTCC 25308: gastroprotection, diarrhea, oxidative stress, cholesterol, adipocyte metabolism.

View the Research →
03

Strain Identity

A clearly identified and deposited probiotic strain: Heyndrickxia coagulans MTCC 25308 and ATCC PTA-126364.

Explore Strain Identity →
04

Grades & Specs

Documented strengths of 200 billion and 300 billion viable spores per gram for different formulation needs.

View Grades & Specs →
[ 03 ] Functional Components

What Bacospore® produces.

Bacospore®'s functional activity is not based on a single standardized phytochemical. The strain produces a set of microbiology-derived components identified in the product overview and associated with intestinal microbial balance.

Class 01

Short-Chain Organic Acids

Produced during microbial metabolism and associated with intestinal environmental support.

Class 02

Bacteriocin-Like Substances

Microbial substances that may help limit the growth of undesirable organisms.

Class 03

Exopolysaccharides

Biologically active microbial polymers associated with probiotic functionality and microbial interactions.

Class 04

Amylases & Proteases

Enzymes associated with the digestion of carbohydrates and proteins and improved nutrient utilization.

[ 04 ] Health Benefits

Six research-backed positioning areas.

Benefit · 01

Healthy Intestinal Microflora

Helps maintain a balanced gastrointestinal microbial environment.

Benefit · 02

Digestive Comfort

Supports normal digestion, stool consistency and gastrointestinal function.

Benefit · 03

Gut-Barrier Integrity

Helps maintain epithelial and intestinal-barrier function.

Benefit · 04

Nutrient Digestion & Absorption

Produces enzymes and metabolites associated with digestive efficiency.

Benefit · 05

Immune Function

Supports interactions between the intestinal microbiome and normal immune responses.

Benefit · 06

Antioxidant & Metabolic Support

Preclinical findings indicate antioxidant activity and effects on cholesterol and adipogenic pathways.

[ 05 ] Data Reference · STH-25308

Multifunctional preclinical evidence.

Strain-specific preclinical evidence

80.4%
Ulcer Inhibition
Ethanol-induced gastric ulcer model
26.6%
Diarrhea Inhibition
Castor-oil model at 200 mg/kg
85.4%
Collagenase Inhibition
Assay at 200 µg/mL
97.72%
Cholesterol Reduction
Assay at 1,000 µg/mL
54.19
IC₅₀ (µg/mL)
Comparative antioxidant activity

In an ethanol-induced gastric-ulcer model, Bacospore® administration significantly reduced the ulcer index. Laboratory evaluations also reported dose-dependent antioxidant activity and cholesterol reduction. These findings support further investigation of Bacospore® for gastrointestinal, metabolic and cellular-protection applications.

Read the Full Research Evidence →
[ 06 ] Resource Library

Technical documents for your evaluation.

Doc · 01

Product Presentation

Overview of Bacospore®, strain identity, benefits and formulation positioning.

Download PPT →
Doc · 02

Research Dossier

Studies covering gastroprotection, antidiarrheal activity, antioxidant, cholesterol and metabolic pathways.

Download Dossier →
Doc · 03

Product Specification

Viable spore count, physical properties, heavy-metal limits and microbiological requirements.

Download Spec →
Doc · 04

Sample COA

A representative batch-quality document for technical evaluation.

Download Sample COA →
Doc · 05

Technical Data Sheet

Taxonomy, morphology, microbial characteristics, available strength and storage guidance.

Download TDS →
Doc · 06

Videos & Scientific Media

Fermentation, spore stability, gastrointestinal delivery and mechanism-of-action animations.

View Videos →
Star Hi Herbs Pvt. Ltd. manufacturing facility interior
[ 07 ] Manufacturer

Manufactured by Star Hi Herbs Pvt. Ltd.

Star Hi Herbs Pvt. Ltd. develops and manufactures standardized botanical ingredients, nutraceutical products and probiotic preparations for the dietary-supplement and functional-food industries.

Bacospore® is supported by the company's research team in Bengaluru and manufactured at Star Hi Herbs Pvt. Ltd., Unit-2 SEZ, located in the Pharma SEZ at Hassan, Karnataka, India. Fermentation is identified as the manufacturing process and India as the country of origin.

ISO 9001:2015GMP CertifiedHassan SEZ · Karnataka
Visit Star Hi Herbs →
[ 08 ] Technical Enquiry

Request a Bacospore® sample or quote.

Evaluate Bacospore® for your next dietary supplement, functional food or nutraceutical formulation. Please include your target viable count, dosage form, annual quantity and destination market so our technical and commercial teams can recommend the appropriate grade.